After a brutal war of aggression by Zol on Akhafa, a mysterious disease - black wolf fever - suddenly spread and brought the war to an abrupt end. But many years later, rebels from Akhafa want to spread the deadly disease further into the country with the help of wild dogs carrying the virus.
Meanwhile, Van tries to find a better life with the young orphan Yuna. Yet the simple life they long for is still a long way off. Evil forces pursue the two, for Van has survived the bite of an infected animal and seems to be resistant to the fever.
Sae, a rebel assassin, and the doctor Hossal try to find Van. While Hossal tries to create an antidote using Van's blood, Sae wants to prevent just that. Will Van and Yuna manage to escape the danger?